Abstract Background Neuroblastoma (NB) patients with amplified MYCN often face a grim prognosis and are resistant to existing therapies, yet MYCN protein is considered undruggable.KAP1 (also named TRIM28) plays a crucial role in multiple biological activities.This study aimed to investigate the relationship between KAP1 and MYCN in NB.Methods Trans
Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice.Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long.The time is now to narrow the gap between Wet Shaving what we know and what we do.Clear guidelines exist for
12-pulse Tick Dips rectifier is extensively used in high power rectification, and the delta-connected autotransformer and wye-connected autotransformer are its two most popular phase-shift transformers.This paper compares the 12-pulse rectifiers using the two transformers via calculating the input line current, load voltage, kVA ratings of the two
Visceral pain refers to pain arising from the internal organs and is distinctly different from the expression Wet Shaving and mechanisms of somatic pain.Diseases and disorders with increased visceral pain are associated with significantly reduced quality of life and incur large financial costs due to medical visits and lost work productivity.In spi